Prognyx MCP MCP server

An official read-only MCP server by Prognyx that allows AI tools to query live ClinicalTrials.gov oncology data and search Prognyx's proprietary research briefings. It enables users to compare interventional trials side-by-side, analyze trial landscapes by indication or target, and retrieve sponsor and phase information without requiring an API key or account.

Endpoint and access

No sign-in: your client connects and lists tools immediately, with no account or key.

No sign-inEndpoint checked 2026-10-05Operated by Prognyx

MCP endpoint (Streamable HTTP)

https://www.prognyx.com/api/mcp

Vendor documentation

What you can do with it

Compare interventional oncology trials side-by-side by sponsor, phase, and outcomes
Search ClinicalTrials.gov for active studies related to specific drug targets or indications
Search Prognyx's archive of published competitive intelligence briefings

Tools advertised by the last live check:

compare_trials
search_registry
search_briefings

Connect from your client

Each snippet registers the same endpoint; pick the client you use.

This server is operated by the named third party. Listing and endpoint checks are not an endorsement or a security audit. Review the operator's permissions, terms, and data handling before connecting. How listings are checked and corrected.

Claude Code

Run this once in a terminal. It registers a Streamable HTTP server. Use --scope project to write .mcp.json for the repo.

Claude Code configuration

claude mcp add --transport http prognyx-mcp https://www.prognyx.com/api/mcp

Codex

Run this once. Codex stores MCP servers in ~/.codex/config.toml (or .codex/config.toml in a trusted project).

Codex configuration

codex mcp add prognyx-mcp --url https://www.prognyx.com/api/mcp

Cursor

Merge this server into .cursor/mcp.json in your project, then enable prognyx-mcp in your MCP settings.

Cursor configuration

{
  "mcpServers": {
    "prognyx-mcp": {
      "url": "https://www.prognyx.com/api/mcp"
    }
  }
}

Cline

Merge this into cline_mcp_settings.json (Cline → MCP Servers → Configure). The type must be streamableHttp for a remote HTTP server.

Cline configuration

{
  "mcpServers": {
    "prognyx-mcp": {
      "type": "streamableHttp",
      "url": "https://www.prognyx.com/api/mcp",
      "disabled": false
    }
  }
}

VS Code

Merge this server into .vscode/mcp.json. Use MCP: List Servers to start prognyx-mcp and inspect its tools.

VS Code configuration

{
  "servers": {
    "prognyx-mcp": {
      "type": "http",
      "url": "https://www.prognyx.com/api/mcp"
    }
  }
}

Gemini CLI

Run this once. It writes .gemini/settings.json in the current project; pass --scope user for ~/.gemini/settings.json.

Gemini CLI configuration

gemini mcp add --transport http prognyx-mcp https://www.prognyx.com/api/mcp

Claude Desktop

Merge this into claude_desktop_config.json (macOS: ~/Library/Application Support/Claude/, Windows: %APPDATA%\Claude\), then restart Claude Desktop.

Claude Desktop configuration

{
  "mcpServers": {
    "prognyx-mcp": {
      "url": "https://www.prognyx.com/api/mcp"
    }
  }
}

Windsurf

Merge this into ~/.codeium/windsurf/mcp_config.json, then refresh MCP in Cascade. Windsurf remote servers use serverUrl, not url.

Windsurf configuration

{
  "mcpServers": {
    "prognyx-mcp": {
      "serverUrl": "https://www.prognyx.com/api/mcp"
    }
  }
}

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